diff --git a/src/applications/meta/xactions/PhabricatorApplicationUninstallTransaction.php b/src/applications/meta/xactions/PhabricatorApplicationUninstallTransaction.php
--- a/src/applications/meta/xactions/PhabricatorApplicationUninstallTransaction.php
+++ b/src/applications/meta/xactions/PhabricatorApplicationUninstallTransaction.php
@@ -80,4 +80,13 @@
     }
   }
 
+  public function shouldTryMFA(
+    $object,
+    PhabricatorApplicationTransaction $xaction) {
+    // Uninstalling an application is a big deal, so we should require MFA
+    // as a precaution similarly to empowering users.
+    // See also https://we.phorge.it/T15490
+    return true;
+  }
+
 }